I appreciate the detail in your support responses but we're are off track in this thread.
The original question should have been, is my agency Toolset license compatible with WP Multisite and you confirmed that it was.
In regards to how I plan to build the templates, I would like to use Divi Builder and other 3rd party elements to create a site template or set of templates integrated with Toolset apps. It would be great it core Toolset app functionality was pre-integrated and available for cloning and customization.
Would something such as this be possible?
You can create Content Templates in Toolset, using Divi Builder to design those content templates. You can also create custom post types, custom taxonomies, custom fields, etc. and connect all these elements in one site in the network. Then you can export those interconnected elements as modules using Toolset Module Manager. When you create a new site in the network, you can import those modules after activating the Toolset Module Manager plugin. This is a fast way to get a site up and running with common post types, templates, taxonomies and custom fields.
More information about Content Templates:
https://toolset.com/documentation/getting-started-with-toolset/create-templates-to-display-custom-posts/
Some best practices for working with Toolset and Divi:
https://toolset.com/documentation/recommended-themes/toolset-divi-integration/