Yes, you can use jQuery, but you if you try to use it directly you will likely experience an error because it won't be available yet at the time the View is added to the page and your code is parsed.
You need to use vanilla JavaScript to wait for the document loaded event before setting up jQuery for use, which you can do as in this example:
document.addEventListener("DOMContentLoaded", function () {
(function ($) {
//jQuery here
$('body').css("border", "5px solid purple");
})(jQuery);
});